The largest science museum in the Western Hemisphere, The Museum of Science and Industry is home to more than 35,000 artifacts and 14 acres of hands-on exhibits. Among the museum's most popular are The Great Train Story, a dynamic model train display; The Coal Mine, a reproduction of an Illinois coal mine that takes you 50 feet to the bottom of a mineshaft; Take Flight, which uses a real 727 plane to explain commercial flights; and Genetics: Decoding Life, which helps you understand the basics of DNA.